PIPELINE

A focused pipeline of regenerative cell therapies.

Our clinical pipeline is centred on indications where stem cell therapy has shown the strongest evidence — knee osteoarthritis and degenerative disc disease — advanced through our Oracle and Delfi AI platforms. Additional programs in neurodegeneration are in preclinical development.

THERAPEUTIC FOCUS

Areas where regenerative medicine can change outcomes.

Musculoskeletal regeneration LEAD

Our primary therapeutic area, addressing osteoarthritis and degenerative disc disease — chronic conditions affecting more than 600 million people globally, with no approved disease-modifying therapies. Both of our active clinical programs sit in this area.

Neurodegeneration EMERGING

iPSC-derived neuronal therapies for Parkinson's disease, building on our cell therapy modality to address one of the highest-unmet-need indications in neurology. Currently in preclinical development.

CLINICAL PIPELINE

Programs in active clinical development.

Both lead programs use autologous stem cell therapy, advanced through Oracle's cell therapy operating system.

Program
Modality
Indication
Phase
Platform
CLL-001
Autologous Stem cells
Knee osteoarthritis
Lead asset; pivotal trial in preparation
PHASE 3
Oracle
CLL-002
Autologous Stem cells
Degenerative disc disease
Phase 2 efficacy data expected within 12 months
PHASE 2
Oracle
CLINICAL EVIDENCE

Validated outcomes from our lead programs.

Peer-reviewed data from our musculoskeletal programs demonstrate significant, sustained reductions in pain — alongside radiographic evidence of tissue regeneration.

PAIN REDUCTION · KNEE OA
−60%
Mean reduction in VAS pain score at 12 months versus active control in osteoarthritis patients receiving intra-articular MSCs.
El-Kadiry et al. BMC Musculoskeletal Disorders, 2022.
PMID 34980045 ↗
DISC REGENERATION · MRI
90%
Of treated discs showed improved or intact structural quality on MRI at 12 months in spinal degenerative joint disease patients.
El-Kadiry et al. Frontiers in Medicine, 2021.
PMID 33816523 ↗
OPIOID CESSATION · BACK PAIN
80%
Of treated patients independently discontinued opioid use within 12 months post-procedure, with no relapse at follow-up.
El-Kadiry et al. Frontiers in Medicine, 2021.
PMID 33816523 ↗

For the full list of peer-reviewed publications, see Our Technology  →

UNDER DEVELOPMENT

Preclinical pipeline.

Our preclinical programs are evaluated end-to-end through Oracle and Delfi before advancing — applying the same decision-graded AI to next-generation indications beyond our current clinical portfolio.

CLL-003
CELL
iPSC-derived dopaminergic neurons
Parkinson's disease — engineered DA-neurons designed to restore dopaminergic signalling. Currently in preclinical development; advancing through Oracle's cell-therapy operating system.
Cell Technologies

A clinical-stage AI-native pharmaceutical company advancing FDA and Health Canada-approved stem cell technology to market, powered by Oracle and Delfi — proprietary platforms purpose-built for the decisions that determine whether new medicines reach patients.

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Our Technology
Pipeline
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Cell Technologies
About
Our Technology
Pipeline
Investors
Contact
About
Our Technology
Pipeline
Investors
Contact